Cucurbituril-X
1,3,5-Tricyclohexyl Cucurbit[6]uril

1,3,5-Tricyclohexyl Cucurbit[6]uril

Basic Information

Product Name1,3,5-Tricyclohexyl Cucurbit[6]uril
CAS Registry NumberAvailable upon request
FormulaC48H54N24O12·10H2O
Molecular Weight1339 g/mol
Purity≥98%
StorageSealed, light-proof, store at room temperature in dry conditions

Specifications & Pricing

SpecificationsPriceStock Status
50mg$490In Stock
100mg$840In Stock
200mg$1,680In Stock
500mg$3,080In Stock

Product Description

Solubility: Excellent water solubility (10 mg/mL). Soluble in acids. Chemical properties: Forms complexes with metal ions and host-guest complexes. Appearance: Colorless or white powder, purity ≥95%

Applications

Enhanced Water SolubilityBiological ApplicationsSupramolecular Chemistry

Technical notes on cyclohexyl cucurbiturils

The cyclohexano-fused series (Cy5CB[5], Cy6CB[6], 1,3,5-Cy3CB[6]) features cyclohexane rings fused to the exterior of the glycoluril units. These substituents extend outward from the cavity, improving solubility and processability primarily by disrupting crystal packing and enhancing solvation, while maintaining cavity dimensions similar to those of the unsubstituted homologues. Consequently, most established host–guest design rules apply directly. The 1,3,5-tricyclohexyl pattern offers an optimal balance between solubility and synthetic accessibility, serving as a common alternative for aqueous workups.

Storage, Solubility, and Handling Guidelines

  • Store sealed, dry, and protected from light at room temperature. For long-term storage, keep at 2–8 °C under dry conditions.
  • Cucurbituril powders are slightly hygroscopic. Reseal immediately after use and record the batch number and opening date.
  • Solubility tips: CB[7] and the modified series dissolve directly in water. For CB[6], first dissolve in formic acid or DMSO, then dilute into the target solvent system.
  • Filter stock host solutions and use them fresh; for binding experiments, record buffer composition, ionic strength, and pH.
  • These materials are for research use only and must not be used in humans, food, pharmaceutical manufacturing, or clinical diagnostics.
  • Batch-specific purity, water content, and spectral data are available upon request prior to ordering.

Selection and further reading