![Symmetrical tetramethyl cucurbit[6]uril](https://material-image.wanwang.xin/1708783130487998/public/a1e443a3-b4c7-4eb3-a50e-7a471a507817.png)
Symmetrical tetramethyl cucurbit[6]uril
Basic Information
Specifications & Pricing
| Specifications | Price | Stock Status | |
|---|---|---|---|
| 500mg | $392 | In Stock | |
| 1g | $560 | In Stock | |
| 5g | $2,520 | In Stock | |
| 10g | $4,480 | In Stock |
Product Description
Solubility: Moderate water solubility; soluble when heated (5-10 mg/mL). Soluble in acids (0.1 M HCl, 50 mg/mL). Chemical properties: Forms complexes with metal ions. Appearance: Colorless or white powder, purity ≥95%
Applications
Technical notes on methylated cucurbiturils
Methylation introduces methyl groups on the glycoluril nitrogen or carbon atoms, weakening intermolecular hydrogen-bond packing and greatly improving water solubility. Symmetrical tetramethyl CB[6] (TMeCB[6]), permethylated CB[5] (Me10CB[5]) and permethylated CB[6] (Me12CB[6]) all allow concentrated aqueous stocks while retaining the rigid cavity and both carbonyl portals, so recognition of cationic and neutral aromatic guests remains comparable to the parent homologues. They suit biological, sensing and materials work in pure water or buffer where an organic co-solvent is undesirable.
Storage, Solubility and Handling Notes
- Store sealed, dry and protected from light at room temperature; for long-term storage keep at 2–8 °C under dry conditions.
- Cucurbituril powders are somewhat hygroscopic — reseal promptly after use and record the batch number and opening date.
- Solubility tips: CB[7] and the modified series dissolve directly in water; for CB[6], dissolve first in formic acid or DMSO, then dilute into the target solvent system.
- Filter stock host solutions and use them freshly prepared; for binding experiments record buffer composition, ionic strength and pH.
- These materials are for scientific research use only and must not be used in humans, food, pharmaceutical manufacturing or clinical diagnostics.
- Batch-specific purity, water content and spectral data are available on request before ordering.
Selection and further reading
- Cucurbit[n]uril homologue property comparisonCavity volume, portal diameter, outer diameter and height — the geometric basis for judging whether a guest can enter the cavity.
- Solubility and application comparison tableWater solubility, typical guests and application areas for each homologue.
- Cucurbituril selection guideSelect by guest size, solvent system, application area and required scale.
- Custom synthesis serviceFor special substitution patterns, specific homologues or larger quantities, submit a custom request.
- Contact the technical team for a quoteGet pricing, batch analytical data and shipping options.

![Permethylated cucurbit[5]uril](https://material-image.wanwang.xin/1708783130487998/public/0aa4a72f-72d9-4a73-813f-ecd2bd4a8b06.png)
![Permethylated cucurbit[6]uril](https://material-image.wanwang.xin/1708783130487998/public/03932b1e-040c-4c8b-8d9b-f6e57f7c7cc8.png)