![Symmetrical tetramethyl cucurbit[6]uril](https://material-image.wanwang.xin/1708783130487998/public/a1e443a3-b4c7-4eb3-a50e-7a471a507817.png)
Symmetrical tetramethyl cucurbit[6]uril
Basic Information
Specifications & Pricing
| Specifications | Price | Stock Status | |
|---|---|---|---|
| 500mg | $392 | In Stock | |
| 1g | $560 | In Stock | |
| 5g | $2,520 | In Stock | |
| 10g | $4,480 | In Stock |
Product Description
Solubility: Moderate water solubility; soluble when heated (5-10 mg/mL). Soluble in acids (0.1 M HCl, 50 mg/mL). Chemical properties: Forms complexes with metal ions. Appearance: Colorless or white powder, purity ≥95%
Applications
Technical notes on methylated cucurbiturils
Methylation adds methyl groups to the glycoluril nitrogen or carbon atoms, disrupting intermolecular hydrogen-bond packing and significantly enhancing water solubility. Symmetrical tetramethyl CB[6] (TMeCB[6]), permethylated CB[5] (Me10CB[5]), and permethylated CB[6] (Me12CB[6]) all support concentrated aqueous stock solutions while preserving the rigid cavity and carbonyl portals. Consequently, their ability to recognize cationic and neutral aromatic guests remains comparable to that of the parent homologues. These derivatives are ideal for biological, sensing, and materials applications in pure water or buffer where organic co-solvents are undesirable.
Storage, Solubility, and Handling Guidelines
- Store sealed, dry, and protected from light at room temperature. For long-term storage, keep at 2–8 °C under dry conditions.
- Cucurbituril powders are slightly hygroscopic. Reseal immediately after use and record the batch number and opening date.
- Solubility tips: CB[7] and the modified series dissolve directly in water. For CB[6], first dissolve in formic acid or DMSO, then dilute into the target solvent system.
- Filter stock host solutions and use them fresh; for binding experiments, record buffer composition, ionic strength, and pH.
- These materials are for research use only and must not be used in humans, food, pharmaceutical manufacturing, or clinical diagnostics.
- Batch-specific purity, water content, and spectral data are available upon request prior to ordering.
Selection and further reading
- Comparison of properties among cucurbit[n]uril homologuesCavity volume, portal diameter, outer diameter, and height — the geometric criteria for determining whether a guest can enter the cavity.
- Solubility and application comparison tableWater solubility, typical guest molecules, and application areas for each homologue.
- Cucurbituril selection guideSelect by guest size, solvent system, application area, and target scale.
- Custom synthesis serviceFor special substitution patterns, specific homologues, or larger quantities, submit a custom request.
- Contact the technical team for a quoteGet pricing, batch analytical data, and shipping options.
![Permethylated cucurbit[5]uril](https://material-image.wanwang.xin/1708783130487998/public/0aa4a72f-72d9-4a73-813f-ecd2bd4a8b06.png)
![Permethylated cucurbit[6]uril](https://material-image.wanwang.xin/1708783130487998/public/03932b1e-040c-4c8b-8d9b-f6e57f7c7cc8.png)