Cucurbit[7]uril

Basic Information

Product NameCucurbit[7]uril

CAS Registry Number259886-50-5

FormulaC₄₂H₄₂N₂₈O₁₄·10H₂O

Molecular Weight1342 g/mol

Purity≥98%

StorageSealed, light-proof, store at room temperature in dry conditions

Specifications & Pricing

Specifications	Price	Stock Status
500mg	$280	In Stock
1g	$420	In Stock
5g	$1400	In Stock
10g	$2800	In Stock

Product Description

Solubility: Moderate water solubility (5–10 mg/mL). Solubility increases with temperature; forms gel readily at 10⁻⁴ M. Dissolves well in acids. Chemical properties: Forms complexes with metal ions and host-guest complexes. Appearance: Colorless or white powder, purity ≥95%. Note: 99% grade is a light yellow powder.

Applications

Drug DeliveryFluorescence SensingHost-Guest Chemistry

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Technical notes on CB[7]

CB[7] is the most widely used homologue: cavity ≈279 Å³, portal ≈5.4 Å — an excellent match for ferrocene, adamantane, aromatic ammonium salts, and the hydrophobic motifs of many drug molecules, with association constants reaching 10⁹–10¹² M⁻¹. Unlike CB[5] and CB[6], CB[7] is readily water-soluble and can be stored at tens of mmol/L, making it the default host for drug solubilization and controlled release, fluorescence and electrochemical sensing, molecular switching, and biological recognition. Note that buffer ionic strength and pH strongly affect apparent binding constants.

Storage, Solubility, and Handling Guidelines

Store sealed, dry, and protected from light at room temperature. For long-term storage, keep at 2–8 °C under dry conditions.
Cucurbituril powders are slightly hygroscopic. Reseal immediately after use and record the batch number and opening date.
Solubility tips: CB[7] and the modified series dissolve directly in water. For CB[6], first dissolve in formic acid or DMSO, then dilute into the target solvent system.
Filter stock host solutions and use them fresh; for binding experiments, record buffer composition, ionic strength, and pH.
These materials are for research use only and must not be used in humans, food, pharmaceutical manufacturing, or clinical diagnostics.
Batch-specific purity, water content, and spectral data are available upon request prior to ordering.