Cucurbit[6]uril

Basic Information

Product NameCucurbit[6]uril

CAS Registry Number80262-44-8

FormulaC₃₆H₃₆N₂₄O₁₂·10H₂O

Molecular Weight1176 g/mol

Purity≥98%

StorageSealed, light-proof, store at room temperature in dry conditions

Specifications & Pricing

Specifications	Price	Stock Status
1g	$22	In Stock
5g	$98	In Stock
10g	$168	In Stock
100g	$1,260	In Stock

Product Description

Solubility: Poor water solubility (10⁻³–10⁻⁴ M). Soluble in strong acids (1 M HCl ~10 mg/mL; 3 M HCl ~50 mg/mL). Chemical properties: Forms complexes with metal ions and host-guest complexes with organic guests. Appearance: Colorless or white powder, purity ≥95%

Applications

Molecular RecognitionDrug ReleaseSupramolecular Assembly

Add to Inquiry Contact to Buy

Technical notes on CB[6]

CB[6] was the first cucurbituril homologue studied systematically. With a cavity of ≈164 Å³ and a portal diameter of ≈3.9 Å, it exhibits textbook-level affinity for short alkyl diammonium salts and protonated aliphatic amines. This makes CB[6] the most widely used reference host in host–guest studies, as well as a classic container for supramolecular assembly, crystal engineering, and confined reactions. CB[6] has poor water solubility and typically requires formic acid, acidic media, or heating for dissolution; 1-g to 100-g packs are suitable for groups preparing assemblies in bulk or using it as an additive.

Storage, Solubility, and Handling Guidelines

Store sealed, dry, and protected from light at room temperature. For long-term storage, keep at 2–8 °C under dry conditions.
Cucurbituril powders are slightly hygroscopic. Reseal immediately after use and record the batch number and opening date.
Solubility tips: CB[7] and the modified series dissolve directly in water. For CB[6], first dissolve in formic acid or DMSO, then dilute into the target solvent system.
Filter stock host solutions and use them fresh; for binding experiments, record buffer composition, ionic strength, and pH.
These materials are for research use only and must not be used in humans, food, pharmaceutical manufacturing, or clinical diagnostics.
Batch-specific purity, water content, and spectral data are available upon request prior to ordering.