Cucurbituril-X
Cucurbit[8]uril

Cucurbit[8]uril

Basic Information

Product NameCucurbit[8]uril
CAS Registry Number259886-51-6
FormulaC48H48N32O16·10H2O
Molecular Weight1508 g/mol
Purity≥98%
StorageSealed, light-proof, store at room temperature in dry conditions

Specifications & Pricing

SpecificationsPriceStock Status
500mg$280In Stock
1g$420In Stock
5g$1,400In Stock
10g$2,520In Stock

Product Description

Solubility: Very poor water solubility (10⁻⁴–10⁻⁵ M). Soluble in strong acids (6 M HCl ~10 mg/mL). Chemical properties: Forms complexes with metal ions and host-guest complexes. Appearance: Colorless or white powder, purity ≥95%.

Applications

Ternary ComplexationSupramolecular PolymersPhotochemistry

Technical notes on CB[8]

CB[8] features a cavity of ≈479 ų and a portal of ≈6.9 Å. It is best known for binding two guests simultaneously as a 1:1:1 ternary complex—typically an electron acceptor (methyl viologen) paired with an electron donor (naphthol, aromatic amino acid, or peptide fragment). This reversible crosslink enables self-healing hydrogels, supramolecular polymers, stimuli-responsive materials, and photochemical control. CB[8] has moderate water solubility; warm to dissolve and filter while hot. Since ternary binding involves two sequential equilibria, determine binary and ternary constants separately.

Storage, Solubility, and Handling Guidelines

  • Store sealed, dry, and protected from light at room temperature. For long-term storage, keep at 2–8 °C under dry conditions.
  • Cucurbituril powders are slightly hygroscopic. Reseal immediately after use and record the batch number and opening date.
  • Solubility tips: CB[7] and the modified series dissolve directly in water. For CB[6], first dissolve in formic acid or DMSO, then dilute into the target solvent system.
  • Filter stock host solutions and use them fresh; for binding experiments, record buffer composition, ionic strength, and pH.
  • These materials are for research use only and must not be used in humans, food, pharmaceutical manufacturing, or clinical diagnostics.
  • Batch-specific purity, water content, and spectral data are available upon request prior to ordering.

Selection and further reading